I've upgrade my Linux desktop a few days ago on Fedora 15 and tried to install Skype from the official rpms without any luck. All I've got is: skype: error while loading shared libraries: libXss.so.1: cannot open shared object file: No such file or directory
To solve the issue apart from the normal depedencies you will need to install the 32 library of qt4 along with a few more depending your already installed libraries. Each time that you receiving an error just try to satisfy the depedency:
[root@pappous stelios]# yum -C provides libQtGui.so.4
Loaded plugins: langpacks, presto, refresh-packagekit
1:qt-x11-4.7.2-8.fc15.i686 : Qt GUI-related libraries
Repo : fedora
Other : libQtGui.so.4
and at the end Skype will work!